New Publication! Congratulations to Anusha and Manik on their work in Trends in Analytical Chemistry!

Congratulations to 3rd-year student, Anusha Vajrala, and 4th-year student, Manik Reddy on their recent co-first author publication in Trends in Analytical Chemistry!

Multiplexed protein diagnostics for complex infection-associated conditions: Advancing proof-of-concept biosensors toward clinical deployment

Abstract: Infection-associated health conditions are often diagnostically overlooked, largely due to non-specific overlapping symptoms, and the limited availability of multiplexed assays. Their diagnosis is further exacerbated by differences in underlying patient-to-patient physiology, which results in considerable heterogeneity in disease presentation and diagnostic levels of candidate biomarkers. Multiplexed protein detection offers one approach to addressing confounding patient heterogeneities, providing a functional snapshot of current disease states. Commercial assays compatible with such disease profiling are often time-consuming and require trained operators, restricting their utility in rapid clinical decision making. Recently, miniaturized, multiplexed protein diagnostics have emerged in hopes of addressing these limitations but have largely been restricted to proof-of-concept demonstrations. The path towards deployable technologies is often not fully appreciated during fundamental method development, which can lead to downstream problems in translation and adoption. This review emphasizes the role of multiplexed protein-based diagnostics as exploratory and translational research tools for infection-associated health conditions.

Click here for the full link!

Congratulations to Anusha and Camila for being accepted to miLEAD!

Congratulations to 3rd-year students Anusha Vajrala and Camila Gonzalez for being accepted into the miLEAD consulting group at UofM! miLEAD is a non-profit, professional development organization in collaboration with the local business community. Graduate students and post doctoral fellows in the organization serve as consultants and partner with small businesses and local companies to provide assistance on market analysis, competitive landscape, value propositions, regulatory research, and more. 

Recently, 3rd-year student Anusha Vajrala published a piece with miLEAD titled “The Impact of Total Laboratory Automation on the Global Health Diagnostics Market”, where she highlights current market trends in Total Laboratory Automation (TLA) and how TLA integration in biotechnology companies can benefit a variety of stakeholders.

Read the article here!

2025 Alum|NUM and URAN|UM event and Karle Symposium recap!

The annual Alumni Networking at UMich (Alum|NUM) and Undergraduate Research and Networking at UMich (URAN|UM) event fosters connections between undergraduate researchers and alumni in academia and industry through scientific research presentations. Rising fourth-year student, Ayush Chitrakar, served as Co-President for the event, while rising fourth-year student, Lindsay Heagle, and third-year students, Hannah Morris and Anusha Vajrala, contributed as members of the organizing committee.

Bailey Lab members attended the Alum|NUM and URAN|UM event and presented at the Isabella & Jerome Karle Symposium last week! Invited speakers spanned both industry and academia, with Dr. Favid Fenn (PPG) giving the plenary lecture and Dr. Erin Baker (UNC Chapel Hill) giving the keynote lecture. Additional events included visiting faculty and industry-led panels, professional development activities, graduate student presentations, and poster sessions.

Representing the Bailey Lab at the Karle Symposium were rising fourth-year student, Manik Reddy, and rising third-year students, Hannah Morris and Anusha Vajrala. Rising fourth-year, Lindsay Heagle, and rising third-years, Camila Gonzalez, Hannah Morris, and Anusha Vajrala, were on the organizing committee for this symposium.

Thank you to all of the student organizers, sponsors, visiting faculty and industry professionals for making this a successful event. We look forward to participating in the Karle Symposium next year!

Hanyu gives a talk at Agilent!

The 4th annual Agilent Measurement Science Symposium was held on May 16, 2025. This symposium aims to celebrate the cutting edge technologies and developments that drive scientific measurement. The Bailey Lab was represented by rising 4th-year PhD candidate, Hanyu Zheng. Hanyu presented a talk titled “Impacts of Synthesis Conditions on Membrane Protein Incorporation into Nanodiscs.” Congratulations, Hanyu!