Publications

2017

  • A guide to quantitative biomarker assay development using whispering gallery mode biosensors, H.M. Robison, R.C. Bailey, Current Protocols in Chemical Biology, 2017, 9, 158–173. 
    DOI: 10.1002/cpch.23
     
  • Multiplexed silicon photonic sensor arrays enable facile characterization of coagulation protein binding to Nanodiscs with variable lipid content, E.M. Muehl, J.M. Gajsiewicz, S.M. Medfisch, Z.S.B. Wiersma, J.H. Morissey, and R.C. Bailey, Journal of Biological Chemistry2017, in Press.
    DOI: 10.1074/jbc.M117.800938
  • Microfluidic Platform for Efficient Nanodisc Assembly, Membrane Protein Incorporation, and Purification, J.H. Wade, J.D. Jones, I.L. Lenov, C.M. Riordan, S.G. Sligar and R.C. Bailey, Lab on a Chip, 2017, Accepted Manuscript
    DOI: 10.1039/C7LC00601B

  • The K-Channel: A Multi-Functional Architecture for Dynamically Re-Configurable Sample Processing in Droplet Microfluidics, S.R. Doonan, R.C. Bailey, Analytical Chemistry, 2017, 89(7), 4091–4099
    DOI: 10.1021/acs.analchem.6b05041

  • Polymer Brush-Modified Microring Resonators for Partition-Enhanced Small Molecule Chemical Detection, A.L.D. Stanton, K.A. Serrano, P.V. Braun, R.C. Bailey, Chemistry Select2017, 2(4), 1521-1524
    DOI: 10.1002/slct.201700082

  • Electrolyte Gradient-Based Modulation of Molecular Transport through Nanoporous Gold Membranes, D.A. McCurry, R.C. Bailey Langmuir2017, 33(6), 1552-1562
    DOI: 10.1021/acs.langmuir.6b04128

2016

  • PCR-free, Multiplexed Expression Profiling of microRNAs using Silicon Photonic Microring Resonators, R.M. Graybill, C.S. Para, R.C. Bailey Analytical Chemistry2016, 99(21), 10347-10351
    DOI: 10.1021/acs.analchem.6b03350
  • Multiplexed Cancer Biomarker Detection Using Chip-Integrated Silicon Photonic Sensor Arrays, A.L. Washburn, W.W. Shia, K.A. Lenkeit, S.-H. Lee, R.C. Bailey Analyst2016, 141, 5358-5365
    DOI: 10.1039/C6AN01076H
  • Nanoporous Gold Membranes as Robust Constructs for Selectively Tunable Chemical Transport, D.A. McCurry, R.C. Bailey, Journal of Physical Chemistry C2016, 120 (37), 20929–20935
    DOI: 10.1021/acs.jpcc.6b02759
  • Applications of Optical Microcavity Resonators in Analytical Chemistry, J.H. Wade, R.C. Bailey, Annual Reviews in Analytical Chemistry20169, 1-25.
    DOI: 10.1146/annurev-anchem-071015-041742
  • Increasing the strength and bioactivity of collagen scaffolds using customizable arrays of 3D-printed polymer fibers, L.C. Mozden, R. Rogers, J.M. Banks, R.C. Bailey, B.A. Harley, Acta Biomaterialia201633, 25-33.
    DOI: 10.1016.j.actbio.2016.02.004
  • Emerging Biosensing Approaches for microRNA Analysis, R.M. Graybill, R.C. Bailey, Analytical Chemistry201688, 431-450.
    DOI: 10.1021/acs.analchem.5b04679
  • Development and validation of an immunosensor for monocyte chemotactic protein 1 using a silicon photonic microring resonator biosensing platform, E. Valera, W.W. Shia, R.C. Bailey, Clinical Biochemistry2016, 49, 121-126.
    DOI: 10.1016/j.clinbiochem.2015.09.001

2015

  • Rapid, Multiplexed Phosphoprotein Profiling Using Silicon Photonic Sensor Arrays, J.H. Wade, A.T. Alsop, N.R. Vertin, H. Yang, M.D. Johnson, R.C. Bailey, ACS Central Science, 2015, 1(7), 374-382.
    DOI: 10.1021/acscentsci.5b00250
  • Dangling phosphine complexes: Phosphine exchange in pentacarbonyl tungsten complexes of bis(diphenylphosphinomethyl)phenylphosphine, C.P. Gamage, R.C. Bailey, E.A. Keiter, J.R. Kuczynski, K.A. Wheeler, C.L. Stern, D.E. Brandt, R.L. Keiter, Journal of Organometallic Chemistry2015794, 258-265.
    DOI: 10.1016/j.jorganchem.2015.07.017
  • Bioanalytical chemistry: Eavesdropping on interactions, E. Valera, R.C. Bailey, Nature Chemistry, 2015, 7, 767-779.
    DOI: 10.1038/nchem.2355
  • A tunable, photoreactive hydrogel system to probe synergies between mechanical and biomolecular cues on adipose-derived mesenchymal stem cell differentiation, J.M. Banks, B.A. Harley, R.C. Bailey, ACS Biomaterials Science & Engineering2015, 1(8), 718-725. 
    DOI: 10.1021/acsbiomaterials.5b00196
  • Magnetically-actuated, bead-enhanced silicon photonic immunosensor, E. Valera, M. S. McClellan, R.C. Bailey, Analytical Methods, 20157, 8539 - 8544.
    DOI: 10.1039/C5AY01477H

2014

  • The combined effects of matrix stiffness and growth factor immobilization on the bioactivity and differentiation capabilities of adipose-derived stem cells, J.M. Banks, L.C. Mozdzen, B.A. Harley, R.C. Bailey, Biomaterials, 2014, 35(32), 8951-8959.
    DOI: 10.1016/j.biomaterials.2014.07.012
  • Strategies to balance covalent and non-covalent biomolecule attachment within collagen-GAG biomaterials, J.C. Pence, E.A. Gonnerman, R.C. Bailey, B.A. Harley, Biomaterials Science, 2014, 2, 1296-1304.
    DOI: 10.1039/C4BM00193A
  • Photopatterning of VEGF within collagen-GAG scaffolds can induce a spatially confined response in human umbilical vein endothelial cells, A.T. Alsop, J.C. Pence, D.W. Weisgerber, B.A. Harley, R.C. Bailey, Acta Biomaterialia, 2014, 10(11), 4715-4722.
    DOI: 10.1016/j.actbio.2014.07.002
  • Collagen Scaffold Arrays for Combinatorial Screening of Biophysical and Biochemical Regulators of Cell Behavior, S.R. Caliari, E.A. Gonnerman, W.K. Grier, D.W. Weisgerber, J.M. Banks, A.T. Alsop, J.-S. Lee, R.C. Bailey, B.A. Harley, Advanced Healthcare Materials, 2014, 4(1), 58-64.
    DOI: 10.1002/adhm.201400252
  • Benzophenone-based photochemical micropatterning of biomolecules to create model substrates and instructive biomaterials, A.J. Turgeon (A.T. Alsop), B.A. Harley, R.C. Bailey, Methods in Cell Biology, 2014, 121, 231-42. 
    DOI: 10.1016/B978-0-12-800281-0.00015-4
  • Refractive Index-Based Detection of Gradient Elution Liquid Chromatography using Chip-Integrated Microring Resonator Arrays, J.H. Wade, R.C. Bailey, Analytical Chemistry, 2014, 86, 913-919.
    DOI: 10.1021/ac4035828

2013

  • Bromelain Decreases Neutrophil Interactions with P-selectin, but not E-Selectin, In Vitro by Proteolytic Cleavage of P-selectin Glycoprotein Ligand-1, J.M. Banks, C.M. Herman, R.C. Bailey, PLoS One, 2013, 8(11): e78988. 
    DOI: 10.1371/journal.pone.0078988
  • Subpicogram Per Milliliter Detection of Interleukins Using Silicon Photonic Microring Resonators and an Enzymatic Signal Enhancement Strategy, J.T. Kindt, M.S. Luchansky, A.J. Qavi, R.C. Bailey, Analytical Chemistry, 2013, 85, 10653-10657
    DOI: 10.1021/ac402972d
  • Biomolecular analysis with microring resonators: applications in multiplexed diagnostics and interaction screening, J.T. Kindt, R.C. Bailey, Current Opinion in Chemical Biology, 2013, 17, 818-826.
    DOI: 10.1016/j.cbpa.2013.06.014
  • Interfacing Lipid Bilayer Nanodiscs and Silicon Photonic Sensor Arrays for Multiplexed Protein-Lipid and Protein-Membrane Protein Interaction Screening, C.D. Kuhnline Sloan, M.T. Marty, S.G. Sligar, and R.C. Bailey, Analytical Chemistry, 2013, 85, 2970-2976.
    DOI: 10.1021/ac3037359

2012

  • Single Domain Antibodies for the Detection of Ricin Using Silicon Photonic Microring Resonator Arrays, Winnie W. Shia and R.C. Bailey, Analytical Chemistry, 2012, 85, 805-810.
    DOI: 10.1021/ac3030416
  • Chaperone Probes and Bead-Based Enhancement Improve the Direct Detection of mRNA Using Silicon Photonic Sensor Arrays, J.T. Kindt and R.C. Bailey, Analytical Chemistry, 2012, 84, 8067-8074.
    DOI: 10.1021/ac3019813
  • Nonlinear Analyte Concentration Gradients for One-Step Kinetic Analysis Employing Optical Microring Resonators, M.T. Marty, C.D. Kuhnline Sloan, R.C. Bailey and S.G. Sligar. Analytical Chemistry, 2012, 84, 5556-5564.
    DOI: 10.1021/ac300478f
  • Label-free, Multiplexed Detection of Bacterial tmRNA Using Silicon Photonic Microring Resonators, O. Scheler, J.T. Kindt, A.J. Qavi, L. Kaplinski, B. Glynn, T. Barry, A. Kurg and R.C. Bailey, Biosensors & Bioelectronics, 2012, 36, 56-61. DOI: 10.1016/j.bios.2012.03.037
  • High-Q Optical Sensors for Chemical and Biological Analysis, M.S. Luchansky and R.C. Bailey, Analytical Chemistry, 2012, 84, 793-821.
    DOI: 10.1021/ac2029024
  • Label-Free Virus Detection Using Arrays of Silicon Photonic Microring Resonators, M.S. McClellan, L.L. Domier, and R.C. Bailey, Biosensors & Bioelectronics, 2012, 31, 388-392.
    DOI: 10.1016/j.bios.2011.10.056

2011

  • Naturally Amplified Player for Biosensing: tmRNA to the Rescue, O. Scheler, L. Kaplinski, B. Glynn, R.C. Bailey, A. Kurg, Procedia Engineering, 2011, 25, 1549-1552.
    DOI: 10.1016/j.proeng.2011.12.383
  • Label-free, Multiplexed Biomolecular Analysis Using Arrays of Silicon Photonic Microring Resonators, A.L. Washburn, M.S. Luchansky, M.S. McClellan, and R.C. Bailey, Procedia Engineering, 2011, 25, 63-66.
    DOI: 10.1016/j.proeng.2011.12.016
  • Rapid, Multiparameter Profiling of Cellular Secretion Using Silicon Photonic Microring Resonator Arrays, M.S. Luchansky and R.C. Bailey, Journal of the American Chemical Society, 2011, 133, 20500-20506.
    DOI: 10.1021/ja2087618
  • Nanostructured Substrates for Optical Sensing, J.W. Kemling, A.J. Qavi, R.C. Bailey, and K.S. Suslick, Journal of Physical Chemistry Letters, 2011, 2, 2934-2944. *selected for cover image
    DOI: 10.1021/jz201147g
  • Real-time Monitoring of Surface-Initiated Atom Transfer Radical Polymerization Using Silicon Photonic Microring Resonators: Implications for Combinatorial Screening of Polymer Brush Growth Conditions, F.T. Limpoco and R.C. Bailey, Journal of the American Chemical Society, 2011, 133, 14864-14867.
    DOI: 10.1021/ja205358g
  • Quantitative Photochemical Immobilization of Biomolecules on Planar and Corrugated Substrates: A Versatile Strategy for Creating Functional Biointerfaces, T.A. Martin, C.T. Herman, M.C. Michael, G.K. Potts, and R.C. Bailey, ACS Applied Material & Interfaces, 2011, 3, 3762-3771.
    DOI: 10.1021/am2009597
  • Isothermal Discrimination of Single-Nucleotide Polymorphisms via Kinetic Desorption and Label-Free Detection of DNA using Silicon Photonic Microring Resonator Arrays, A.J. Qavi, T.M. Mysz, and R.C. Bailey, Analytical Chemistry, 2011, 83, 6827-6833.
    DOI: 10.1021/ac201659p
  • Anti-DNA:RNA Antibodies and Silicon Photonic Microring Resonators: Increased Sensitivity for Multiplexed microRNA Detection, A.J. Qavi*, J.T.Kindt*, M.A.Gleeson, and R.C. Bailey, Analytical Chemistry, 2011, 83, 5949-5956.
    DOI: 10.1021/ac201340s
  • Probing Dynamic Cell-Substrate Interactions using Photochemically Generated Surface-Immobilized Gradients: Application to Selectin-Mediated Leukocyte Rolling, C.T. Herman, G.K. Potts, M.C. Michael, N.V. Tolan, R.C. Bailey, Integrative Biology, 2011, 3, 779-791.
    DOI: 10.1039/c0ib00151a
  • Sensitive on-chip detection of a protein biomarker in human serum and plasma over an extended dynamic range using silicon photonic microring resonators and sub-micron beads, M.S. Luchansky, A.L. Washburn, M.S. McClellan, and R.C. Bailey, Lab on a Chip, 2011, 11, 2042-2044.
    DOI: 10.1039/c1lc20231f
  • DNA-encoding to Improve Performance and Allow Parallel Evaluation of the Binding Characteristics of Multiple Antibodies in a Surface-Bound Immunoassay Format, A.L. Washburn, J. Gomez, and R.C. Bailey, Analytical Chemistry, 2011, 83, 3572-3580.
    DOI: 10.1021/ac200317z
  • The generation of biomolecular patterns in highly porous collagen-GAG scaffolds using direct photolithography, T.A. Martin, S. Caliari, B.A. Harley, R.C. Bailey, Biomaterials, 2011, 32, 3949-3957.
    DOI: 10.1016/j.biomaterials.2011.02.018
  • Silicon photonic microring resonator arrays for scalable and multiplexable bioanalysis, M.S. Luchansky, A.L. Washburn, A.J. Qavi, J.T. Kindt, M.S. McClellan, and R.C. Bailey, Proc. SPIE, 2011, 7888, 788802. (Invited submission)
    DOI: 10.1117/12.880492
  • Multiplexed evaluation of capture agent binding kinetics using arrays of silicon photonic microring resonators, J.-Y. Byeon, R.C. Bailey, Analyst, 2011, 136, 3430-3433.
    DOI: 10.1039/c0an00853b
  • Photonics-on-a-Chip: Integrated Waveguides as Enabling Detection Elements for Lab-on-a-Chip Biosensing Applications, A.L. Washburn and R.C. Bailey, Analyst, 2011, 136, 227-236.
    DOI: 10.1039/C0AN00449A

2010

  • Informative Diagnostics for Personalized Medicine, R.C. Bailey, Nature Chemical Biology, 2010, 6, 857-859.
    DOI: 10.1038/nchembio.488
  • Sizing up the Future of MicroRNA Analysis, A.J. Qavi, J.T. Kindt, and R.C. Bailey, Analytical & Bioanalytical Chemistry, 2010, 398, 2535-2549.
    DOI: 10.1007/s00216-010-4018-8
  • Efficient Bioconjugation of Protein Capture Agents to Biosensor Surfaces Using Aniline-Catalyzed Hydrazone Ligation, J.-Y. Byeon, F.T. Limpoco, and R.C. Bailey, Langmuir, 2010, 26, 15430-15435.
    DOI: 10.1021/la1021824
  • Characterization of the Evanescent Field Profile and Bound Mass Sensitivity of a Label-Free Silicon Photonic Microring Resonator Biosensing Platform, M.S. Luchansky, A.L. Washburn, T.A. Martin, M. Iqbal, L.C. Gunn, and R.C. Bailey, Biosensors & Bioelectronics, 2010, 26, 1283-1291.
    DOI: 10.1016/j.bios.2010.07.010
  • Multiplexed Detection and Label-Free Quantitation of MicroRNAs Using Arrays of Silicon Photonic Microring Resonators, A.J. Qavi and R.C. Bailey, Angew. Chem. Intl. Ed., 2010, 49, 4608-4611. (* Selected by the Editors as a “Hot Paper”; Highlighted in the cover story of the September 2010 issue of Genome Technology magazine.)
    DOI: 10.1002/anie.201001712
  • Silicon Photonic Microring Resonators for Quantitative Cytokine Detection and T-cell Secretion Analysis, M.S. Luchansky and R.C. Bailey, Anal. Chem., 2010, 82, 1975-1981.
    DOI: 10.1021/ac902725q
  • Label-Free Biosensor Arrays based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation, M. Iqbal, M.A. Gleeson, B. Spaugh, F. Tybor, W.G. Gunn, M. Hochberg, T. Baehr-Jones, R.C. Bailey, and L.C. Gunn, J. Sel. Topics Quantum Electron., 2010, 16, 654-661.
    DOI: 10.1109/JSTQE.2009.2032510
  • Quantitative, Label-Free Detection of Five Protein Biomarkers Using Arrays of Silicon Photonic Microring Resonators, A.L. Washburn, M.S. Luchansky, A.L. Bowman, and R.C. Bailey, Anal. Chem., 2010, 82, 69-72. (* Highlighted in the December 21, 2009 issue of Chemical & Engineering News.)
    DOI: 10.1021/ac902451b

2009

  • Label-Free Quantitation of a Cancer Biomarker in Complex Media Using Silicon Photonic Microring Resonators, A.L. Washburn, L.C. Gunn, and R.C. Bailey, Anal. Chem., 2009, 81, 9499-9506. (* Highlighted in the January 2010 issue of Photonics Spectra.)
    DOI: 10.1021/ac902006p
  • New Multiparameter Bioanalytical Technologies for Applications in Personalized Medicine, Drug Discovery, and Fundamental Biology, R.C. Bailey, Bioanalysis, 2009, 1, 1043-1047.
    DOI: 10.4155/bio.09.101
  • Direct Biophotolithographic Method for Generating Substrates with Multiple Overlapping Biomolecular Patterns and Gradients, C.R. Toh, T.A. Fraterman, D.A. Walker, and R.C. Bailey, Langmuir, 2009, 25, 8894-8898.
    DOI: 10.1021/la9019537
  • Modular Nucleic Acid Assembled p/MHC Microarrays for Multiplexed Sorting of Antigen-Specific T Cells, G.A. Kwong, C.G. Radu, K. Hwang, C.J. Shu, C. Ma, R.C. Koya, B. Comin-Anduix, S.R. Hadrup, R.C. Bailey, O.N. Witte, T.N. Schumacher, A. Ribas, and J.R. Heath, J. Am. Chem. Soc., 2009, 131, 9695-9703.
    DOI: 10.1021/ja9006707
  • Label-Free Technologies for Quantitative Multiparameter Biological Analysis, A.J. Qavi, A.L. Washburn, J.-Y. Byeon, and R.C. Bailey, Anal. & Bioanal. Chem., 2009, 394, 121-135. (Invited article as part of "'Young Investigators in Analytical and Bioanalytical Science" issue; ** Selected as the "Hot Article" for the issue)
    DOI: 10.1007/s00216-009-2637-8
  • A Robust Silicon Photonic Platform for Multiparameter Biological Analysis, R.C. Bailey, A.L. Washburn, A.J. Qavi, M. Iqbal, M. Gleeson, F. Tybor, and L.C. Gunn, Proc. SPIE, 2009, 7220, 72200N. (Invited submission)
    DOI: 10.1117/12.809819

2008 & Earlier

  • Active Learning in the Introductory Graduate Student Analytical Chemistry Course: Getting Students to "Think Analytically", A. Scheeline and R.C. Bailey, in Active Learning: Models from the Analytical Sciences (ed. Mabrouk, P. A.) 248-258 (American Chemical Society, Washington, DC, 2007)
  • DNA-Encoded Antibody Libraries: A Unified Platform for Multiplexed Cell Sorting and Detection of Genes and Proteins, R.C. Bailey, G. Kwong, C.G. Radu, O.N. Witte, and J.R. Heath, J. Am. Chem. Soc., 2007, 129, 1959-1967. (* Highlighted in Nature Methods, Analytical Chemistry, and ACS Chemical Biology)
  • A Non-Oxidative Approach toward Chemically and Electrochemically Functionalizing Si(111), R.D. Rohde, H.D. Agnew, W.-S. Yeo, R.C. Bailey, and J.R. Heath, J. Am. Chem. Soc., 2006, 128, 9518-9525.
  • Sensing via Optical Interference, R.C. Bailey, M. Parpia and J. T. Hupp, Materials Today, 2005, 8, 46-52. (Invited article)
  • Detection of Chemical Species Using Ultraviolet Microdisk Lasers, W. Fang, D.B. Bucholz, R.C. Bailey, J.T. Hupp, R.P.H. Chang, and H. Cao, Appl. Phys. Lett., 2004, 85, 3666-3668.
  • Micropatterned Diffraction Gratings: A Versatile New Class of Chemical and Biological Sensors, R.C. Bailey and J.T. Hupp, Lab Plus International, 2004, 18, 14-17. (Invited article)
  • Synthesis and Optical Properties of "Branched" Gold Nanocrystals, E. Hao, R.C. Bailey, J.T. Hupp, G.C. Schatz, and S. Li, Nano. Lett., 2004, 4, 327-330.
  • Optical Properties of Metal Nanoshells, E. Hao, S. Li, R.C. Bailey, S. Zou, G.C. Schatz, and J.T. Hupp, J. Phys. Chem. B, 2004, 108, 1224-1229.
  • Permeable, Microporous Polymeric Membrane Materials Constructed from Discrete Molecular Squares, M.H. Keefe, J.L. O'Donnell, R.C. Bailey, S.T. Nguyen, and J.T. Hupp, Adv. Mater., 2003, 15, 1936-1939.
  • Real-Time Multicolor DNA Detection with Chemoresponsive Diffraction Gratings and Nanoparticle Probes, R.C. Bailey, J.-M. Nam, C.A. Mirkin, and J.T. Hupp, J. Am. Chem. Soc., 2003, 125, 13541-13547.
  • Micropatterned Polymeric Gratings as Chemoresponsive Volatile Organic Compound Sensors: Implications for Simultaneous Analyte Detection and Identification via Diffraction-Based Sensor Arrays, R.C. Bailey and J.T. Hupp, Anal. Chem., 2003, 75, 2392-2398.
  • Large-Scale Resonance Amplification of Optical Sensing of Volatile Compounds with Chemoresponsive Visible-Region Diffraction Gratings, R.C. Bailey and J.T. Hupp, J. Am. Chem. Soc., 2002, 124, 6767-6774.
  • Photonic Lattices as Diffraction Based Chemical Sensors, R.C. Bailey, B.C. Tzeng, X. Dang, G.A. Mines, K.A. Walters, and J.T. Hupp, in Chemical and Biological Sensors and Analytical Methods II, M. Butler, P. Vanysek and N. Yamazoe, Eds., The Electrochemical Society Proceedings, Pennington, NJ, 2001, pp. 511-520.
  • Assembly of Micropatterned Colloidal Gold Thin Films via Microtransfer Molding and Electrophoretic Deposition, R.C. Bailey, K.J. Stevenson, and J.T. Hupp, Adv. Mater., 2000, 12, 1930-1934.
  • Vibrational Spectra and Heat Capacity of Methane, and the Speed of Sound, R. Tennis, R. Bailey, and G. Henderson, J. Chem. Ed., 2000, 77, 1634-1636.