C&EN Highlights the Lab's Work on LTBI Diagnostics


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Nearly a quarter of the world’s population has latent tuberculosis infection (LTBI). These people don’t have symptoms of the infection because the TB bacteria living inside them are dormant. In about 10% of those people, the bacteria will wake up, but diagnosing latent TB and predicting who is at risk for reactivating is hard.

A team led by Ryan C. Bailey of the University of Michigan and Patricio Escalante of Mayo Clinic reports an assay that reveals diagnostic signatures that doctors could use to both diagnose latent TB and evaluate a patient’s reactivation risk.

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